Chamomile vs Melatonin: An Honest Comparison For Sleep, Side Effects & More!

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Last Updated on December 14, 2022 by theworldofsleepstaff

Chamomile and melatonin are two popular supplements used to promote better sleep. And luckily both are effective in helping people fall asleep faster, stay asleep longer, and improve the overall quality of their sleep.

However, some key differences and similarities between these two supplements should be considered when determining the most beneficial one for you.

For example melatonin’s function in the sleep-wake cycle makes it a good choice for those who struggle to fall asleep and stay asleep, while chamomile’s calming properties could make it the better choice for those who suffer from anxiety-related sleep problems.

However that’s just scratching the surface when it comes to the differences, similarities, and science when considering whether chamomile or melatonin is best for you.

Luckily, this guide will help you understand the pros and cons of chamomile and melatonin so you can make the most informed decision. Let’s get started!

Disclaimer: Please note that this is general information and does not substitute for professional advice from your doctor or pharmacist. Always consult with a professional healthcare provider before using chamomile or melatonin.


  1. Which Is Better For Sleep?
  2. The Similarities
  3. The Differences
  4. Can I Take Chamomile & Melatonin Together?
  5. How The Side Effects Compare
Depressed man suffering from insomnia lying in bed

Chamomile vs Melatonin: which is better for sleep?

Chamomile and melatonin are both used to improve sleep. While neither of the two is a substitute for proper sleep hygiene, they do have different roles in improving sleep quality.

Chamomile has traditionally been used as a herbal remedy to promote relaxation and reduce stress. It can be taken as a tea, extract, or supplement. The active ingredient in chamomile is an antioxidant called apigenin which is thought to be responsible for its calming effects. Rachbauer

Melatonin is a hormone produced by the pineal gland in the brain that helps regulate sleep cycles. It is available as a supplement and can help induce sleep in the evening. It often prescribed by doctors for sleep issues.

Melatonin is known to help improve sleep quality, reduce the time it takes to fall asleep, and increase alertness during the daytime.

When deciding which is better for improving sleep, the type of sleep problems you have should be considered.

For example, melatonin may be more beneficial if you have difficulty falling or staying asleep as it can help regulate your natural sleep-wake cycle. However, chamomile may be a better option if your problem is more related to stress or anxiety since it has calming properties that can help reduce those symptoms before bed.

Ultimately, the best way to improve sleep quality is still through proper sleep hygiene, such as sticking to a regular sleeping schedule and avoiding screens before bed.

Recommended: 30 Tips On How To Get Better Sleep Naturally

White bottle and pills, letters Melatonin, alarm clock and sleep mask on light grey background. Sleeping backdrop Concept melatonin, insomnia and good night. Top view

Chamomile vs Melatonin For Sleep: The Similarities

Between these two sleep aids, there are several similarities.

1. Effects On Sleep Quality

Both Chamomile and Melatonin can positively affect sleep quality, reducing the time taken to fall asleep and increasing the total amount of time spent in restful sleep.

The thing that works for both of these supplements is that they target the body’s natural sleep cycle to help promote better, longer and more restful sleep.

A young brunette woman sleeping in white bed,

2. Lack Of Significant Side Effects

The good news is that no known significant side effects are associated with either chamomile or melatonin; although this needs verification.

So as long as these supplements are taken in moderation and as directed by a doctor, there shouldn’t be any severe side effects.

If you want to know more about the side effects of either chamomile or melatonin, it is best to speak with a doctor or pharmacist to learn more about the risks associated with taking these supplements. We also cover some of the known side effects further below.

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3. Dosing

The dosing for chamomile and melatonin are similar, depending on the person’s individual needs. Both can be taken in various forms, such as pills, tinctures, or teas, and should be taken shortly before bedtime.

It is best to take the lowest dose that works and gradually increase it if needed for optimal results. If you are having trouble sleeping or have any questions about dosing and safety, it is best to speak with a doctor or pharmacist before taking any supplements.

Melatonin, the word is laid out on a blue background of tablets. Tablets, hormone and excipients to improve sleep. Galaganov

4. Cost

Both chamomile and melatonin are affordable supplements, costing around the same amount.

Depending on the form of supplement taken, prices may vary, but overall they are generally relatively inexpensive compared to other sleep aids.

This makes them an attractive option for those who want a natural and affordable way to improve their sleep quality.

With these two natural supplements, there is potential for good sleep quality and a generally improved sense of wellbeing. However, it is essential to note that everyone’s body reacts differently, so what works for one person may not work for another. Therefore, it is always best to speak with your doctor about any supplements you are considering taking before doing so.

Small glass bottle with essential roman chamomile oil on the old wooden background. Chamomile flowers, close up. Aromatherapy, spa and herbal medicine ingredients.

Chamomile vs Melatonin For Sleep: The Differences

As usual, there will always be differences between natural remedies and medications. In this case, the differences between chamomile and melatonin for sleep are pretty straightforward:

1. One Is A Plant; The Other A Hormone

Chamomile is a naturally occurring plant that has been used for centuries as a herbal remedy to help with sleep. It contains compounds called flavonoids, which have antioxidant and anti-inflammatory properties.

Research suggests that chamomile can help reduce anxiety, promote relaxation and provide mild sedation. However, it does not contain melatonin, a hormone naturally produced by the body necessary for healthy sleep patterns.

With melatonin, however, you supplement your body’s natural supply with a pill form of the hormone.

In addition, because melatonin is an exogenous hormone, it can work more quickly and efficiently to help regulate sleep-wake cycles and improve sleep quality. It has even been beneficial for jet lag and other sleep disorders.

Man harvesting chamomile flower heads on the meadow. Yankovets

2. Different Side Effects

Chamomile is generally safe to use, with few side effects reported. However, some people may experience allergic reactions or digestive discomfort when taking large doses of chamomile.

On the other hand, melatonin can cause headaches, dizziness and sleep disturbances in some people. It is also important to note that too much melatonin can be dangerous, so it’s essential to take the recommended dosage as instructed by your doctor or healthcare provider.

3. Their Sleep Promoting Effects

Another critical difference between chamomile and melatonin is the duration of their sleep-promoting effects.

While chamomile may improve sleep quality, its effects are typically short-lived, lasting for a few hours. Melatonin, on the other hand, can have more long-term benefits when taken regularly over time.

The duration differs because chamomile reduces anxiety and promotes relaxation, while melatonin increases the body’s production of the hormone necessary for healthy sleep.

Sleeping woman in bed at night in dark bedroom. Vesalainen

Can I Take Chamomile And Melatonin Together?

The answer to this question is that it depends. In general, melatonin and chamomile can be taken together. However, it is essential to consider the particular circumstances of your situation to determine if taking them together will be beneficial or detrimental.

First, you should ensure that each supplement’s doses are appropriate for your needs. If you take too much of either supplement, it could cause adverse side effects.

If you are considering taking melatonin and chamomile together, discussing the risks and benefits with your healthcare provider is essential.

Additionally, it would help if you talked to a pharmacist before combining any prescription medications or supplements with chamomile or melatonin. In some cases, certain combinations of supplements may interact unexpectedly, which can be dangerous to your health.

Finally, it is essential to keep in mind that chamomile and melatonin are both sedative substances. Taking too much of either could cause drowsiness, dizziness, confusion and depression. Therefore, it is essential to use caution when taking them together and to make sure that you are monitoring your reactions carefully.

Ultimately, the best action would be to consult your healthcare provider before taking any combination of supplements or medications. They can help you determine if taking chamomile and melatonin together is safe for you.

curly haired woman sleeping in bed. healthy sleep concept. dice composed in melatonin word. and glass of water on bedside table. melatonin and circadian rhythms. Panova

How The Side Effects Compare


The known side effects are:

1. Allergy: Some people may experience an allergic reaction to chamomile, such as rashes, hives, and swelling of the face, lips or tongue.

2. Stomach upset: Chamomile can cause stomach upset and nausea in some people.

3. Blood thinning: This herb can act as a blood thinner and should be avoided by people taking anticoagulants or those with a bleeding disorder.

4. Interactions: Chamomile can interact with other medications, including blood pressure and diabetes medication. It’s important to talk to your doctor before using chamomile if you’re on any medications

5. Pregnancy: Chamomile has been used for centuries as a herbal remedy for pregnant women. However, there is not enough research to confirm its safety during pregnancy. Therefore, it’s best to consult your doctor if you’re pregnant or breastfeeding before taking chamomile.

6. Sun sensitivity: Some people may experience increased sensitivity to the sun when using chamomile, so it’s essential to wear sunscreen if you’re outside

7. Drowsiness: Chamomile can cause drowsiness and should not be taken before driving or operating heavy machinery. It is also best avoided when taking sedative medications as the effects may be increased

8. Skin irritation: Some people may experience skin irritation from the topical use of chamomiles, such as in a cream or ointment. It’s best to test it on a small patch of skin before use

To avoid any possible interactions or side effects, you must talk to your doctor if you are taking any medication or have any medical condition before using chamomile. Also, if you experience any unusual symptoms, stop using chamomile and immediately contact your doctor.


The known side effects are:

1. Headache: Melatonin can cause headaches in some people.

2. Drowsiness: This herb can cause drowsiness and may affect motor skills, so it should be avoided when operating machinery or driving a vehicle

3. Nausea: Some people may experience nausea when taking melatonin.

4. Depression: Melatonin has been linked to depression in some people.

5. Interactions: Melatonin can interact with other medications, such as blood pressure or diabetes medication, so it is essential to talk to your doctor before taking it

6. Pregnancy and Breastfeeding: There is not enough research to confirm the safety of melatonin during pregnancy or breastfeeding. It is best to consult with your doctor before using this herb if you are pregnant or breastfeeding

7. Allergies: Some people may experience an allergic reaction when taking melatonin, such as rashes, hives, and swelling of the face, lips or tongue.